Small lumps in the Achilles tendon are sometimes caused by high cholesterol levels, resulting in cholesterol deposits in the tendon itself. Aside from treating cholesterol itself, treatment for Xanthomas involves taking a biopsy of the lesion but leaving the nodules intact.

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| Excessive training, such as running long distances without rest, places repeated stress on the foot and ankle. The result can be stress fractures and muscle/tendon strains. |
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